The Effectiveness of a 6-Month Nutrition Intervention on Lowering Fasting Glucose and 8OHdG Levels in Prediabetic People Living with HIV (PLWH) in the MASH Cohort


Alicia Sneij*, Adriana Campa, Marianna Baum, Fatma Huffman, Florence George, Mary Jo, Sabrina Sales-Martinez, Leslie Seminario and Jacqueline Hernandez-Boyer

The rate of prediabetes in people living with HIV (PLWH) is 2-3 times higher than in the general population. Nutrition interventions have been effective in lowering diabetes risk in people with prediabetes in the general population, but this has not yet been shown in PLWH. The objective of this study was to assess the effectiveness of a 6-month randomized, controlled nutrition intervention for prediabetic PLWH. Participants (N=38) were randomized into the intervention group (n=20) or the control group (n=18). Inclusion criteria were being HIV+, prediabetic defined by the American Diabetic Association standards, 18 years of age and older, controlled HIV viral load, and not using glucose altering medications. Participants randomized into the intervention group met once a month for 1 hour to receive individualized medical nutrition therapy, nutrition counseling and nutrition education; participants in the control group received educational material at baseline. Outcome variables were collected for all participants at baseline and end of the study between 2017-2018 and analyzed 2018-2019. We found significant improvements in fasting blood glucose (p=0.03), body mass index (p=0.03) and oxidative stress (p=0.04) in the intervention group when comparing their 6-month values to those at baseline; while differences between baseline and end of the intervention were not observed in the control group, with significance set at p<0.05. The results from this intervention support the notion that a nutrition intervention is effective in lowering diabetes risk by significantly lowering fasting blood glucose, body mass index and oxidative stress in PLWH who are prediabetics, who are at greater risk for diabetes and cardiovascular disease than the general Best YouTube to MP3 converter. Download MP3 from YouTube for Free. Download Mp3 songs for free Download mp3 songs online at Mp3 Converter, watch high quality online music videos watch and download free songs of the highest quality. Listen to songs online here comfortably without any annoying advertisements. Easy to use and free MP3 downloader. YouTube To MP3 download in seconds using the best YouTube to MP3 converter. YouTube Mp3 Get the latest song by simply typing the latest artist or song title in the Search menu. Mp3 file format with 128 - 320 Kbps bitrate converted from YouTube videos. read at this blog